Refolution of the cryogenic storage rooms

CRYOGENIC STORAGE ROOMS CRYOGENIC STORAGE ROOMS
Turnkey, customised low-temperature storage rooms with air (R729) as a refrigerant for flexible use from -40 °C to -160 °C - planned and implemented to meet your requirements.

Introduction Storage rooms

Our storage rooms are designed to meet customer requirements and given space with storage systems, safety, loading and unloading concepts. They consist of special industrial panels with PU foam filling, with optional integrated vacuum panels, which are mechanically stable enough for extreme temperatures and achieve a sufficient insulating effect. For the low-temperature rooms, we use the flexible cold air chillers from Mirai Intex, which can flexibly realise temperatures from -30 °C to -110 °C (optionally up to -160 °C). Appropriate airlock systems are integrated for energy optimisation and ice fog reduction.

The machine control system is implemented with an S7 and our developed safety concepts and can be expanded to meet customer requirements, such as GMP Audit Trail with GAMP5. The equipment in the storage rooms is integrated, from temperature monitoring and LED lighting to shelving or rail systems.

Planning, consulting and logistics concept

We discuss and analyse your low-temperature logistics in order to optimally develop and integrate the storage space. Relevant topics here are the storage capacity, the stored goods, the stored goods temperature, the storage temperature with tolerances, the containers, the shelving, the transport units, the climatic conditions such as humidity, etc. We also discuss the transport routes and loading with you. We also work with you to develop redundancy and safety concepts, such as emergency power supply or PPE for low-temperature clothing.

DEEP-PERATURE STORAGE ROOMS Interior view
DEEP-PERATURE STORAGE ROOMS Interior view
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Technical details of the storage room

  • Insulation

    The insulation is realised with tried-and-tested polyurethane insulation elements from Teledoor. These can be optimised with integrated vacuum panels depending on requirements. When cold, the elements contract and the outer shell remains warm. This results in mechanical stress, which is all the greater the higher the temperature difference and the higher the temperature of the chamber. Our chambers are reinforced with hook fasteners so that the chambers remain mechanically stable even after many temperature changes. We also check all our installations with a thermal imaging camera to optimise penetrations, such as for cable penetrations.

  • Floor structure

    A level floor is required for the floor structure. We can also realise this with screed work as an option. The actual floor of the cryogenic storage room consists of a vapour-tight foil, 20 mm Stryodor panels and a self-regulating heating system. This prevents the storage room from freezing due to freezing groundwater and the associated damage to the building. The actual floor is then placed on top of the heating and can be fitted with appropriate heavy-duty profiles and vacuum plates in the floor slab depending on the load profile and temperature requirements. The floor itself is fitted with non-slip, fully welded stainless steel plates for easy cleaning.

  • Control system

    The solution includes the complete control system, including control cabinet. The control system is realised via an S7 from Siemens and can optionally be equipped with a redundant, high-availability control system, additional backup control system and audit trail (GAMP 5). The control system can be integrated into the building management system (BMS) using the classic interfaces. In addition, faults can be detected and rectified at an early stage via remote maintenance if required.

  • Lighting

    The lighting is realised with robust special LEDs. Unlike normal LED lights, these remain bright at low temperatures and can be switched on and off. This enables very efficient and safe operation. They are also battery-buffered so that the room can be left safely even in the event of a power failure.

Reliable, durable, efficient and safe for people and the environment  
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Technical versions

  • Refrigeration technology

    We carry out a detailed cooling load calculation based on your requirements and then use the appropriate, efficient refrigeration technology with only natural refrigerants. For low temperatures below -40 °C, the cold air refrigeration technology from Mirai Intex with only air (R729) is used in the open version. With its mechanical defrosting, this ensures homogeneous temperature distribution, dry storage air with a dew point reduction of up to 20 °C and constant temperatures without defrosting cycles. For airlock cooling and cold water generation, we use CO₂ (R744) or propane (R290) for cooling, depending on requirements. These natural refrigerants are free from political regulations, such as the F-Gas Regulation.

  • Security

    We work with you to develop the optimum safety and service concept. Our storage rooms are characterised by non-slip floors, impact protection, bright lighting and low fog and ice formation due to the airlocks and mechanical de-icing. In particular, our dead man's switch, which starts a timer after the door is opened and sounds an alarm when it expires, has proved its worth. This concept can also be supplemented with an optional panic button. With the escape route and pressure equalisation valves, the rooms can always be exited safely.

Your advantages at a glance

Future-proof
Future-proof

Air as a refrigerant is free of charge, free of regulations and safe. The systems are robust and specially designed for low temperatures.

High reliability
High reliability

Proven technology - Made in Germany. Low-wear and redundant.

Flexible
Flexible

Customised design with freely selectable temperatures during operation.

Efficient
Efficient

Speed-controlled, no vaporiser, expander with energy feedback to the turbo unit, low spec. surface, vacuum insulation and airlock.

Safe for people and the environment
Safe for people and the environment

Natural refrigerant with no high pressures, no toxicity and no flammability. 0 GWP, 0 ODP, 0 TFA. High level of personal protection thanks to dead man's switch, escape routes, low ice mist and non-slip floors.

Low maintenance & durable
Low maintenance & durable

No leak test, air-bearing compressor = no wear, no oil, high-quality insulation.

Oliver Fleischer

HOF Sonderanlagenbau GmbH

Oliver Fleischer · Head of Service / Head of development - department refrigeration technology

Mit Refolution gelingt die Zukunft der Nachhaltigkeit, gepaart mit Effizienz und Weitsicht.
Der Profi für die Zukunft.
Christian Berger

CSL Behring

Christian Berger · Global Director - Process and Technology Owner for Aseptic & Sterility

Refolution supported me in the technical verification of design and dimensioning of a Natural Refrigerant Cooling System for a new Freeze Dryer system.
I was very happy with the immediate support and competence of the Refolution Team. Thanks for your help.
Christian Berger

CSL Behring

Christian Berger · Directeur mondial - Propriétaire du processus et de la technologie pour l'asepsie et la stérilité

Refolution m'a aidé dans la vérification technique de la conception et du dimensionnement d'un système de refroidissement par réfrigérant naturel pour un nouveau système Freeze Dryer.
J'ai été très heureux de l'assistance immédiate et de la compétence de l'équipe Refolution. Merci pour votre aide.
Oliver Fleischer

HOF Sonderanlagenbau GmbH

Oliver Fleischer · Responsable du service / Responsable du développement - département de la technologie de la réfrigération

Avec Refolution, l'avenir de la durabilité, allié à l'efficacité et à la clairvoyance, est une réussite.
Le professionnel de l'avenir.
Mario Käfer

Octapharma Produktionsgesellschaft Deutschland mbH

Mario Käfer · Spécialiste de la technologie du refroidissement

Refolution nous aide dans la planification et la réalisation dans le domaine des installations frigorifiques, de la récupération de chaleur et de la gestion de l'énergie. Nous sommes très satisfaits de notre collaboration et nous recommandons cette prestation.
Rana Adeel Ahmad

AZENTA LIFE SCIENCES

Rana Adeel Ahmad · Chef de projet de planification et d'amélioration - UE

Refolution nous a aidés à concevoir et à mettre en œuvre une installation d'eau réfrigérée naturelle très efficace sur notre site de Griesheim.
L'équipe nous a impressionnés par son expertise technique approfondie, sa focalisation sur la durabilité et son exécution sans faille du projet.
Nous apprécions vraiment la collaboration professionnelle et l'approche innovante de l'équipe Refolution.
Christian Berger

CSL Behring

Christian Berger · Global Director - Process and Technology Owner for Aseptic & Sterility

Refolution supported me in the technical verification of design and dimensioning of a Natural Refrigerant Cooling System for a new Freeze Dryer system.
I was very happy with the immediate support and competence of the Refolution Team. Thanks for your help.
Oliver Fleischer

HOF Sonderanlagenbau GmbH

Oliver Fleischer · Head of Service / Head of development - refrigeration technology department

With Refolution, the future of sustainability succeeds, coupled with efficiency and foresight.
The professional for the future.
Mario Käfer

Octapharma Produktionsgesellschaft Deutschland mbH

Mario Käfer · Specialist cooling technology

Refolution supports us in the planning and realisation of refrigeration systems, heat recovery and energy management. We are very satisfied with the cooperation and can recommend the service.
Rana Adeel Ahmad

AZENTA LIFE SCIENCES

Rana Adeel Ahmad · Planning and Improvement Project Manager - EU

Refolution supported us in the design and implementation of a highly efficient Natural Refrigerant Chilled Water Plant at our Griesheim site.
The team impressed us with their deep technical expertise, focus on sustainability, and seamless project execution.
We truly appreciate the professional collaboration and the innovative approach of the Refolution team.
Mario Käfer

Octapharma Produktionsgesellschaft Deutschland mbH

Mario Käfer · Specialist cooling technology

Refolution unterstützt uns bei der Planung und Realisierung im Bereich Kälteanlagen, Wärmerückgewinnung und Energiemanagement. Wir sind sehr zufrieden mit der Zusammenarbeit und können die Leistung empfehlen.
Rana Adeel Ahmad

AZENTA LIFE SCIENCES

Rana Adeel Ahmad · Planning and Improvement Project Manager – EU

Refolution supported us in the design and implementation of a highly efficient Natural Refrigerant Chilled Water Plant at our Griesheim site.
The team impressed us with their deep technical expertise, focus on sustainability, and seamless project execution.
We truly appreciate the professional collaboration and the innovative approach of the Refolution team.

Technical details & options

Technical information

Options

Documentation

Videos

  • The storage rooms are planned and designed to meet your individual requirements. This includes the layout as well as the shelving or handling with trolleys or pallets. Storage sizes of up to 500 m³ and temperatures from -30 °C to -160 °C can be realised without any problems. We work with you to develop the logistics, storage, redundancy, safety and service concept.

  • Optionally, you can have the turnkey storage rooms with additional work such as screed leveling, cold water supply, emergency power supply, and much more.

  • Product brochure ULT storage room from Teledoor
  • Video of the cryogenic storage room

References

Suitable applications

Suitable services for your cryogenic storage

Partner

Get in touch with us and let us advise you individually!

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Cornelia Schröder
Cornelia Schröder
Assistant to the management